Michelle Monaghan and Patrick Dempsey Credit: Columbia Pictures

In the new romantic comedy Made of Honor, "dreamy" Patrick Dempsey of Enchanted and "Grey's Anatomy" plays womanizing Tom, the best guy pal of Hannah (Michelle Monaghan of The Heartbreak Kid, Gone, Baby Gone and Mission Impossible III) but it takes her falling in love with a wealthy Scotsman ( TV's "Journeyman" and "Rome's" hot Kevin McKidd) to clue Tom in on the fact that Hannah may just be the one he should never let get away! When Hannah asks Tom to be her "Maid" of Honor, he sees it as a chance to break up her romance and win her back.

Patrick and Michelle hadn't seen each other for a while so there was a little catch up time before our interview in Beverly Hills. Patrick wanted to know about Michelle's recent trip to Australia with hubby Peter White, a graphic designer. Seems Michelle actually did ask a close guy friend to be her "Maid" of honor at her 2005 wedding so she was already living part of the storyline for this film when she joined the project. A perfect match. Read on for a candid chat with the co-stars on juggling, short kilts, falling for your best friend, their own romances and weddings and, from Patrick, what's comin' at us on "Grey's Anatomy".

TeenHollywood: Patrick, how do you see the perfect romantic comedy?