Peter Parker Credit: Sony Pictures

Spider-Man 3 starts off blissfully. All is well in Peter Parkerland as Spidey is the toast of NYC and is about to propose to his Broadway-bound Mary Jane. Of course, in true comic book tradition, it's time to muck up the works with evil meteorite goo and 3, count 'um, 3 supervillains! Ah, what a tangled web they weave!

James Franco as Harry/New Goblin Credit: Sony Pictures

Back to make sure Peter Parker's life doesn't go smoothly, is former pal Harry Osborn (James Franco) who we know blames Peter/Spidey for the death of his dastardly dad. As the New Goblin, he attacks Peter, who is still dressed in street clothes, over Manhattan almost making him drop the engagement ring he's carrying for M.J.! Also, blowing into town is Sandman (Thomas Haden Church), a smalltime crook whose real name is Flint Marko. Peter thinks he's the guy who murdered his beloved Uncle Ben and this guy falls into an experiment turning him into a shape-shifting sand creature who can morph into a variety of shapes including a multi-story giant hulk!

Bryce Dallas Howard as Gwen Stacey and Topher Grace as Eddie Brock/Venom Credit: Sony Pictures

Riding up next in the villain van is Eddie Brock (Topher Grace). Eddie is cocky and thinks he's smooth with the ladies including Peter's hot lab partner Gwen Stacy (Bryce Dallas Howard). He wants Peter's job as photographer at the Daily Bugle. Stay tuned for more on this.